Neuropeptides and inflammation. A somatostatin analog as a selective antagonist of neutrophil activation by substance P
نویسندگان
چکیده
منابع مشابه
Neuropeptides and inflammation: the role of substance P.
The neuropeptide substance P modulates the activities of a number of different leukocytes that characterize both acute and delayed inflammatory responses. Substance P may play a role in the pathogenesis of such diverse diseases as arthritis, asthma, and inflammatory bowel disease.
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A brief overview of recent developments in the substance P field is provided, in addition to a historical introduction. It is emphasized that there are multiple tachykinins and tachykinin receptors and that there are examples of coexistence of several tachykinin peptides and of several tachykinin receptors in single cells, and there is evidence for tachykininergic cotransmission. The distributi...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1992
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780350402